Aidan O'Brien will rely on Snowfall and Broome in the Qatar Prix de l’Arc de Triomphe after Love was declared a non-runner.
The multiple Group One-winning four-year-old was reported by France Galop to have been scratched after developing a temperature.
It is the second year running the Classic heroine has missed the Longchamp showpiece, after being ruled out 12 months ago due to heavy ground.
France Galop said in a statement on Saturday evening: "The filly Love has been declared non-runner with a vet’s certificate after she developed a temperature during Saturday afternoon."
Love had been due to be ridden by Frankie Dettori, with Ryan Moore aboard Snowfall and Yutaka Take partnering Broome.