The Jessica Harrington-trained Alpha Centauri carried the famous colours to victory in Sunday's Irish 1,000 Guineas and Zabriskie, one of seven potential runners for Aidan O'Brien, has been confirmed an intended runner in the Epsom Derby.
The son of Frankel has won just one of his five starts to date, but posted a career-best effort when third in the Dante Stakes at York behind Roaring Lion earlier this month.
Alan Cooper, racing manager for the owners, said: "Aidan says he is an improving horse and Zabriskie gave me the impression at York that he would stay a mile and a half.
"His half-brother Bago (by 1989 Derby winner Nashwan) won the Arc over a mile and a half so there is stamina in the pedigree.
"Zabriskie handled the track at Epsom very well when he ran in the Investec Blue Riband Trial in April (finished sixth).
"The Derby has been the hope for a long time. Aidan has not yet finalised the jockeys for his Derby runners."
The O'Brien squad for this Saturday's feature is headed by red-hot favourite Saxon Warrior.
The Deep Impact colt is odds-on across the board after extending his unbeaten record to four in the 2000 Guineas at Newmarket.
The Ballydoyle handler has also confirmed Delano Roosevelt, Kew Gardens, The Pentagon, Nelson and Rostropovich as he chases a joint-record seventh Derby success.
Dermot Weld's Derrinstown Stud Derby Trial winner Hazapour is the only other Irish-trained contender.
The home team is headed by John Gosden's Roaring Lion, who finished fifth behind Saxon Warrior in the 2000 Guineas.
Masar, who was third in the 2000 Guineas, will bid to become a first Derby winner in the Godolphin colours for Charlie Appleby.
Chester Vase hero Young Rascal is a leading fancy for William Haggas and is set to renew rivalries with the Mark Johnston-trained Dee Ex Bee, who was runner-up on the Roodee.
Harry Dunlop's Lingfield Derby Trial winner Knight To Behold and Gosden's second runner Sevenna Star complete the potential field.