Last year's winner Shanahan's Turn is set to lead trainer Henry de Bromhead's assault on the tote.com Galway Plate on 27 July.
The last horse to claim back-to-back victories in the Ballybrit showpiece was Ansar in 2004-05, but Shanahan's Turn has this year yet to show anything like the form he produced to beat The Paparrazi Kid by five and a half lengths in 2015.
Sadler's Risk, third behind his stablemate in the valuable handicap chase last summer, is also likely to take up the challenge again along with stablemate Home Farm.
"Shanahan's Turn, Sadler's Risk and Home Farm are definites for the Plate and are being aimed at it, and there might be one or two others, too," said De Bromhead.
"Shanahan's Turn is a bit in and out, but has been like that even before the Plate last year.
"He ran a shocker at Killarney and I was actually in two minds about running him in the Plate, but he just came alive. He's a funny guy and is 9lb higher now.
"Sadler's Risk was third last year and had a great run the other day but is also 13lb higher now.
"However, if Road To Riches (the 2014 winner) runs, you'll need to be up around that rating to get in."
