John Gosden has been dealt a blow after being forced to rule So Mi Dar out of the Investec Oaks through lameness.
While the problem is not serious, Gosden is not prepared to take a risk with the Musidora Stakes winner, who looked set to pose a real threat to Aidan O'Brien's 1000 Guineas winner Minding.
The news is a rare reversal of fortune for Gosden, who just days ago appeared to be heading to Epsom with two major chances after the victory of Wings Of Desire in the Dante Stakes.
"It was one of those mornings you get," said Gosden. "She came out of the race great, but this morning she was lame on her left hind.
"I told Andrew and Madeleine (Lloyd-Webber, owners) and got the vet in and she is not right.
"We would call it a one to two out of five to grade it. She may well come right in 10 days, but you cannot go to any major race thinking you can walk for 10 days and suddenly be ready.
"The horse come first and luckily I'm training for proper owner-breeders who understand the game.
"I'm afraid she's a non runner.
"It's a real disappointment. She's a gorgeous filly, she won in great style and we were all looking forward to the Oaks.
"But it's not a little bruise in the foot - it's a little higher up and it's just going to take a little time to come right.
"I'm sure she'll probably be back for the Irish Oaks, but sadly, not Epsom. Such is life. Before I came here I went to see her and she was munching away on her feed."