ITV has signed a four-year deal to become the exclusive terrestrial broadcast partner for British racing from 2017, replacing Channel 4.
Channel 4's last programme will be of the Betfred Challow Hurdle meeting at Newbury on 31 December.
The broadcaster said it wished racing "all the best from 2017".
ITV's landmark first fixture will then be 24 hours later for the New Year's Day card at Cheltenham. The broadcaster is committed to showing nearly 100 days of racing each year, with the Cheltenham Festival, the Crabbie's Grand National meeting at Aintree, the Investec Derby at Epsom and Royal Ascot among the marquee events that will be shown.
In total ITV will show a minimum of 34 fixtures on ITV's main channel and 60 on ITV4, in addition to a magazine programme broadcast each Saturday morning on ITV4, replacing the current Channel 4 version 'The Morning Line'.
Channel 4 itself acquired exclusive broadcast rights in 2013, meaning showcase events such as Royal Ascot and the Derby moved from the BBC.
Much has been made of viewing figures for the sport on Channel 4, which will show Formula One this year after the BBC cut short its contract.
A Channel 4 spokesperson said tonight: "2016 will be an unprecedented year for premium live sport on Channel 4 as it becomes the new terrestrial home of Formula One alongside the Rio 2016 Paralympics and horse racing.
"We are proud of the award-winning coverage we have given to horse racing over the last three decades - and the 90 days of live terrestrial television exposure per year we have offered the sport, backed by significant editorial investment, marketing and programming across our schedules.
"We wish racing all the best from 2017."
ITV has a historical link with racing, going back to the days of the ITV Seven bet, a key component of the Saturday afternoon World of Sport programme.
ITV's coverage moved to Channel 4 in 1985, together with well-known presenters such as Derek Thompson and John McCririck.
