John Gosden's 1000 Guineas fourth The Fugue faces five rivals in the Tattersalls Musidora Stakes at York on Wednesday.
The daughter of Dansili finished off well to pick up minor honours in the Newmarket Classic and she now tries her hand over 10 furlongs in this recognised trial for the Investec Oaks at Epsom next month.
Sariska was the last filly to win both races in 2009.
The Fugue's major rival in the Group Three contest appears to be Aidan O'Brien's Twirl.
The three-year-old was narrowly beaten by subsequent winner Chrysanthemum on her first start of the year at the Curragh in March.
Richard Hannon's Nell Gwyn winner Esentepe needs to bounce back to form after finishing last at Goodwood, while Good Morning Star is turned out again quickly following her shock win in last week's Cheshire Oaks.
Aniseed and Salford Art complete the field.