Triple Cheltenham Gold Cup hero Best Mate is set to return to competitive racing in the Haldon Gold Cup at Exeter on November 1.
That race is a stepping stone to a trip to Haydock's Betfair Cup, the first leg of the new Betfair Million, a three-legged challenge which also takes in the Stan James King George VI Chase and the Gold Cup itself.
But mindful of the injury which ended Best Mate's season back in the spring, bookmakers are dismissive of the chances of the Jim Lewis-owned gelding - who will be 11 by the time he returns to Cheltenham next year - winning all three legs.
Totesport make him a 40-1 chance, while it is 6-1 for any horse to take the sponsors' cash.
Speaking at a media open day at her Berkshire stables, Knight reflected upon the incident on the gallops of Mick Channon which forced the horse to miss his tilt at Cheltenham history.
"Every day it is always in the back of your mind - Terry (Biddlecombe) or I will always make sure at least one of us is watching when he works," she said.
But we don't spend every morning holding our breath. You just hope it doesn't resurface and a lot of horses do it once and then never again.
"There's no cure for it. Just the old-fashioned remedy of lots of fresh air and hoping Mother Nature does her thing.
"He was a very sick horse when he came back from Ireland and he needed more time than we could give him. He was very sorry for himself, coughing and having a mucky nose every day, but by the end of January we were having to start preparing him for Cheltenham again.
"When he was just getting really tuned to run, something gave and he burst a blood vessel. But he has had a nice break now and so far he has done nothing to cause us any concern again.
"One thing we won't ever do again is take him back to that gallop. Horses are like elephants and they remember bad experiences and we won't ask him to remember what happened that morning."
Numbers may have been slightly down on previous gatherings, but enthusiasm for Best Mate was unusually high.
"He's quite fit actually, said Knight as she cast her eye over the gelding as he posed for the cameras like a professional.
"I don't expect him to win at Exeter as I don't think he has got the toe to beat two-milers at their own game, but it would be nice to see him run well."