Padraig Harrington finished in a tie for 10th as Corey Conners pipped Sam Stevens to the Valero Texas Open by one shot.
Ireland's three-time major winner started the day five shots off the overnight lead set by Patrick Rodgers but finished seven adrift of Conners after a one-under-par 71.
Harrington recorded three bogeys and four birdies.
An eagle from Stevens on 17 put it up to Conners but the Canadian, who hit four birdies in a flawless 68, made par on the last to close out victory.
Sam Ryder and Matt Kuchar shared third on 13 under while Rodgers fell to fifth place and 11 under after a 73.
4 years after his first TOUR win, @CoreConn gets it done again @ValeroTXOpen 👏 pic.twitter.com/E8nSmvcqj8
— PGA TOUR (@PGATOUR) April 2, 2023
Conners' only other win on the PGA Tour came at the 2019 edition of the event.
"I was really solid all day," Conners said. "It was a battle out here for sure. The conditions were not easy.
"Struck the ball really, really well, gave myself a lot of looks and kept things under control. It was definitely a battle but a lot of fun. I can't believe I got my second win here."