Shane Lowry was left to rue a double bogey on the 12th as the RBC Heritage slipped away from the Offaly man in South Carolina, and allowed CT Pan to secure his maiden PGA Tour title.
Seamus Power produced a terrific four-under 67 to finish on nine-under in a tie for sixth, a season's best performance that was only three off the winning total. But Lowry will feel bittersweet about a weekend in which he often excelled.
A round of 70 left him on 10-under, two behind the triumphant Pan and in a tie for third with Patrick Cantlay and Scott Piercey.
Lowry began the day one stroke behind Dustin Johnson and hit the front thanks to gains at the second, fifth and sixth.
A bogey at the ninth was followed two more dropped shots at 12 which derailed his bid and, although he picked up a shot at the 14th, he could not eagle the last to force Pan into an extra hole.
Pan took the victory by one shot ahead of Matt Kuchar.
The Taiwan golfer began the final round two shots off Johnson, whose challenge disintegrated after carding seven-over through five holes on the back nine, to claim five birdies and one solitary bogey on his way to a 12-under-par total.
Pan could not match his eagle at the second hole from the third round but managed to be flawless through the front nine, registering birdies at the fifth and ninth.
He picked up further shots at the 10th and 12th to get to 12 under but bogeyed the 15th hole, only to claim the shot back at the next to restore his one-shot advantage over Kuchar, who was already in the clubhouse at 11 under par.
Pan then put his tee shot at the par-three 17th into the greenside bunker, but he held his nerve to scramble par after landing his approach inside three feet.
The 27-year-old narrowly missed out on a birdie at last before enduring a nervous wait for Patrick Cantlay, who moved into contention with five gains despite a double bogey at the fourth.
The American needed a birdie at the 18th to force a play-off, but three-putted for bogey to hand Pan victory.
Power meanwhile was massively buoyed by his showing.
"I didn’t make too many mistakes," the 32-year-old Waterford man told Sky Sports.
"Just the one bogey on one of the easier holes which was disappointing. Overall it was a tricky day so I can’t complain too much.
"The last four or five tournaments have been much better. It was a struggle earlier [in the season], but at the Players [Championship] I started to find some stuff and get a little bit better. It’s been encouraging."