Clare will face Waterford without Shane O'Donnell as the forward continues his recovery following a concussion sustained in training.
The Banner begin their Munster championship campaign with a quarter-final against last year's All-Ireland finalists at Semple Stadium on Sunday (Live on RTÉ One) but the 27-year-old will be absent after suffering the injury almost two weeks ago.
O'Donnell, the hat-trick hero of the 2013 All-Ireland final replay, had hit 1-05 in three league appearances for Clare this season before the injury ruled him out of their final Division 1 game against Kilkenny.
Clare manager Brian Lohan was already planning to be without the services of another veteran of 2013 after defender Patrick O'Connor damaged his cruciate ligament.
Lohan told the Examiner: "We have to abide by the return to play protocols, and he's not ready to come back, so that’s it. Concussion is obviously a very serious matter now and we abide by those rules."
He also revealed that corner-back Aaron Fitzgerald would miss the Waterford match but that Clare are hopeful full-back David McInerney will be fit.
Dublin have lost forward Eamonn Dillon for the entire summer after he picked up an injury in training.
Dillon hit 1-04 in three championship games last winter and his goal threat will be sorely missed in Saturday's Leinster quarter-final against Antrim.
"I'm really disappointed for Trollier himself," manager Mattie Kenny told FM104 after training last night.
"He'd got himself, as he does every year, into great condition. He worked so hard in a difficult period there with the pandemic and Covid.
"He was going really, really well but unfortunately he picked up this injury, that's going to rule him out for this year's inter-county championship.
"He has started his rehab and he hopes to be back with his club in September or October.
"It's a blow for him personally, and it's a blow for us also. He's a top marksman, a top inside-forward and one of the best inside-forwards in the game today. He's been a huge servant for Dublin hurling."
Follow all the championship matches this weekend with our live blogs on RTÉ.ie/sport and the RTÉ News app.
Watch Down v Donegal and Clare v Waterford live on RTÉ One (from 12.55pm) and see highlights of all the weekend's action on The Sunday Game at 9.30pm on RTÉ One.
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