Daryl Gurney will begin his bid for World Darts Championship glory against either Ross Smith or Paul Lim.
The Derry man, who beat world number one Michael van Gerwen in Sunday's Players Championship final, goes straight into round two for the expanded 96-player tournament, which begins in London's Alexandra Palace on 13 December.
Meanwhile, Carlow's Steve Lennon takes on James Bailey of Australia in round one, with the winner facing a clash with Alan Norris.
Brendan Dolan from Fermanagh must deal with Yuanjun Liu of China in order to book a date with England's Joe Cullen.
James Wilson awaits the victor of a tie between Limerick's Willie O'Connor and Holland's Yordi Meeuwisse, while Mickey Mansell from Tyrone must overcome Canada's Jim Long for a second-round match-up with Benito van de Pas.
First-time qualifier Kevin Burness from Down faces Paul Nicholson in his opening game with the prize of a shot at two-time world champion Gary Anderson up for grabs.
Rob Cross will begin the defence of his title against Jeffrey de Zwaan or Nitin Kumar.
The draw for the 2018/2019 William Hill World Darts Championship was made on Monday for darts' biggest-ever event, which will see the field compete for £2.5 million in prize money and the Sid Waddell Trophy live on Sky Sports.
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Under the new, expanded format, the top 32 players from the PDC Order of Merit are seeded and enter at the second round stage.
The first round will feature 32 qualifiers from the ProTour Order of Merit, based on prize money won across 41 non-televised events in 2018, and 32 international qualifiers.
Reigning champion Cross, who shocked the world at last year's event by taking glory on his Alexandra Palace debut, will face a second round test against either World Matchplay semi-finalist De Zwaan or Indian Qualifer Nitin Kumar.
DRAW!— PDC Darts (@OfficialPDC) November 26, 2018
Here is the confirmed draw for the 2018/19 @WilliamHill World Darts Championship! pic.twitter.com/dao4VL2YX4
Van Gerwen will meet Alan Tabern or Australian qualifier Raymond Smith.
Back-to-back World Champion Adrian Lewis will meet Simon Stevenson or rising star Ted Evetts, Peter Wright takes on Spain's Toni Alcinas or New Zealand's Craig Ross, and former champion Raymond van Barneveld will play Matthew Edgar or Lithuania's Darius Labanauskas.
UK and Ireland Women's Qualifier Lisa Ashton will face Dutchman Jan Dekker for the right to play Mervyn King, while Rest of the World Women's Qualifier Anastasia Dobromyslova will take on Ryan Joyce, with the winner to play Simon Whitlock.
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"It's a dream come true, I'm over the moon," said Ashton.
"I’m so chuffed to get through, there were so many top ladies playing in the qualifier and the quality was excellent.
"For me this is a massive win and it’s an amazing opportunity to play the men at Ally Pally.
"It been such an amazing day, everything has been brilliant and to come out on top at the end is everything I could have hoped for.
"We’ll (Anastasia) be flying the flag for ladies darts and hopefully we can do everyone proud."