Back-to-back world champion Gary Anderson will start the defence of his PDC title against Mark Frost.
The Scot - an Alexandra Palace winner against Phil Taylor and Adrian Lewis in the last two years - will face qualifier Frost when the event kicks off on December 15.
In-form world number one and 2014 winner Michael van Gerwen opens against Ross Snook or Kim Viljanen, while 16-time champion Phil Taylor faces either John Bowles or David Platt.
Anderson is bidding to become the third player in history to win three titles in a row, following on from Eric Bristow and Taylor (twice).
Norther Ireland duo Brendan Dolan and Daryl Gurney were both seeded for the draw and Dolan will face Christian Kist with Gurney taking on Jermaine Wattimena.
Meath's Mick McGowan was unseeded and faces a first round clash with Welshman Jamie Lewis.
"It's a really tough draw," Anderson said. "Mark's been around the circuit for a lot of years and is a good player, so I know I'll have to be ready for him but I can't wait to get back to Ally Pally.
"It's a couple of weeks until the tournament starts now and I'll be putting in the work on the board because it would be special if I can win the title for a third time. I'd love to do it again."
The event runs from December 15 through to January 2, with a record first prize of £350,000.