British cyclist Mark Cavendish, riding for the High Road team, prevailed in a sprint for the fourth stage honours of the Tour of Italy at Catanzaro on Tuesday.
Liquigas' Italian rider Franco Pellizotti retained the leader's pink jersey after the 183 kilometre run to this seaside resort on the Giro's first day on the Italian mainland.
Irish professional Philip Deignan (Ag2r La Mondiale) finished as part of the main bunch in 96th position and was classified in the same time as Cavendish.
This was Cavendish's first win in the event and he achieved it by proving too strong in the final push for the line from Germany's Robert Forster and third stage winner, Daniele Bennati of Italy.
The final kilometre was marred by a mass spill which fractured the peloton.
Belgian Rik Verbrugghe took the race by the scruff of the neck from the off, remaining in front until 20km from the line.
The former pink jersey wearer - he wore it briefly in 2001 - had built up an 11 minute cushion at the 110km mark but was eventually reeled in by a chasing pack marshalled by several teams doing the donkey work for their top sprinters.
One of these teams was High Road, whose plan to unleash the 21-year-old Isle of Man-born Cavendish worked to perfection.
This was the budding sprinters' fifth win of the season and he was adding it to his success with compatriot Bradley Wiggins in the men's Madison gold at the world track cycling championships in Manchester in March.
Wednesday's fifth stage is a 203km run between Belvedere Marittimo to Contursi Terme near Salerno.
Official result after the 183-km fourth stage of the Giro d'Italia from Pizzo to Catanzaro on Tuesday
1. Mark Cavendish (Isle of Man / High Road) 4hrs 49mins 09secs
2. Robert Foerster (Germany / Gerolsteiner ) same time
3. Daniele Bennati (Italy / Liquigas )
4. Assan Bazayev (Kazakhstan / Astana )
5. Mirco Lorenzetto (Italy / Lampre )
6. Erik Zabel (Germany / Milram )
7. Robbie McEwen (Australia / Silence - Lotto )
8. Tony Martin (Germany / High Road )
9. Paolo Bettini (Italy / Quick-Step )
10. Koldo Fernandez (Spain / Euskaltel )
Official standings after the 183-km fourth stage of the Giro d'Italia from Pizzo to Catanzaro, on Tuesday
Overall
1. Franco Pellizotti (Italy / Liquigas ) 16hrs 41mins 26secs
2. Christian Vande Velde (U.S. / Slipstream ) +1 sec
3. Danilo Di Luca (Italy / Team LPR ) +7"
4. Morris Possoni (Italy / High Road ) +8"
5. Vincenzo Nibali (Italy / Liquigas )
6. Nicki Sorensen (Denmark / Team CSC ) +17"
7. Kanstantin Sivtsov (Belarus / High Road ) +18"
8. Paolo Savoldelli (Italy / Team LPR ) +19"
9. Andrea Noe (Italy / Liquigas ) +22"
10. Daniele Bennati (Italy / Liquigas ) +24"
Irish:
64. Philip Deignan (AG2R La Mondiale) + 1'50"