Paul Stirling will captain Ireland for Thursday's second One Day International (ODI) against the West Indies in Kingston.
The opening batsman will lead the team for the first time in an ODI, having previously captained the side in six T20 fixtures.
Regular captain, Andrew Balbirnie, has been ruled out of the rescheduled game having tested positive for Covid-19 along with Lorcan Tucker, Simi Singh and Ben White. Head coach David Ripley has also contracted the coronavirus.
Stirling previously contracted Covid-19 during the United States leg of the current tour and as a result, missed out on the first ODI of the Sabina Park series.
The second ODI between West Indies and Ireland will resume on Thursday after the scheduled match was postponed due to Covid-19 cases.
The third and final game of the series will be played on Sunday at Sabina Park. First ball is 2.30pm Irish time in both games.
The rescheduling occurred following five cases, as well as injuries, in the Ireland camp, leaving their squad depleted.
The one-off CG Insurance T20 International has been cancelled to allow for this revised schedule and to avoid impact on the West Indies team's travel plans and subsequent fixtures.
These ODI matches form part of the ICC World Super League with both teams having the opportunity to win points to be one of the top seven teams, excluding hosts India, to gain automatic qualification for the 2023 ICC Men’s Cricket World Cup.
West Indies lead the three-match series 1-0 following their 24-run victory in the first ODI on Saturday.