Ireland all-rounder Alex Cusack will miss next month's one-day international against England due to a back injury.
The two teams face off at Malahide on 3 September but the hosts will be without one of their most experienced players after the Clontarf seamer was ruled out.
Cusack has played 138 games since 2007, taking 141 wickets and scoring 2205 runs.
Coach Phil Simmons said: "It's certainly disappointing for Alex to miss the game as he's an important player for us, particularly in the power-plays. However, we have strength in depth now and it'll give one of the other guys a chance to shine."
Speaking about next month's fixture, Simmons told Cricket Ireland that over 7,000 tiuckets had been sold already.
"It’s going to the biggest match ever held in Ireland, and there will be a fantastic atmosphere at the new international venue at Malahide.
"It’s my home town and I know just how much of a buzz there is around the place to have the Ashes winners coming here. It’ll be a magnificent occasion, and hopefully we’ll give the Irish fans another day to remember.”