Jacques Kallis starred with bat and ball as South Africa inflicted a heavy defeat on Pakistan in the first One-Day International of five between the sides.
First they posted a formidable total of 392 for six - the sixth highest in ODI history - and then quickly got out Pakistan's frontline batsmen.
Pakistan's tailenders showed some defiance to prolong the match and reduce the victory margin but the hosts still ran out winners by 164 runs.
Kallis was top-scorer with an unbeaten 88 for the Proteas and then took three wickets for 34.
Pakistan never looked likely to reach their victory target of 393.
Openers Mohammad Hafeez and Kamran Akmal put on 27 before Hafeez fell for 21 with Graeme Smith taking the catch off the bowling of Makhaya Ntini.
Akmal soon followed for 13 with Ashwell Prince taking the catch off the bowling of Shaun Pollock.
Shahid Afridi went for 17 as he was caught by Andre Nel off Ntini who also captured Younis Khan for 13, caught and bowled.
Afridi then got involved in an altercation with a spectator as he climbed the steps of the pavilion.
Muhammad Yousuf and Inzamam-ul-Haq seemed to represent the last hope for the tourists.
Yousuf made a quick 39 including 19 off one over but played one stroke too many when he holed out to Smith off Nel's bowling.
Inzamam went without further addition to the score when he hooked a Kallis ball to substitute fielder Andrew Hall on the square leg boundary to depart for 15.
Abdul Razzaq went for six with Robin Peterson taking the catch of Kallis who then removed Rana Naved-ul-Hasan for a duck with Mark Boucher taking the catch.
Shoaib Malik and Mohammad Sami then put on 73 for the ninth wicket in a dogged stand that lasted nearly 20 overs before Sami was easily caught by Boucher after skying an attempted slog off Peterson.
Malik went on to complete his 50 and finished unbeaten on 52 as last man Mohammad Asif skied the ball into the hands of Boucher to become last man out for two.
Earlier, all the South African batsmen except Loots Bosman and Justin Kemp made hay as they battered a depleted Pakistan attack.
With injured trio Shoaib Akhtar, Umar Gul and Shabbir Ahmed all out of contention and Danish Kaneria surprisingly dropped, the Proteas batsmen took full advantage.
Openers AB De Villiers and Smith led the way with an opening stand worth 140 which ended after 18.2 overs when Smith was stumped by Akmal off Hafeez.
Smith had made 72 and had cracked 15 fours in his 21st ODI 50 and his departure brought Bosman to the crease.
He struck just one four before falling to the Akmal-Hafeez combination again to only his third ball with Akmal this time taking a catch after an outside edge.
Another 23 runs were added to the total before De Villiers went for 67 with Naved-ul-Hasan taking the catch at deep midwicket off Afridi.
It was a welcome return to form for De Villiers who had struggled in the recent Test series between the sides and will be pleased with his fourth ODI 50.
He struck eight fours and two sixes.
Prince joined Kallis at the crease and he made 39 before becoming the fourth wicket to fall with Afridi claiming his second scalp and Razzaq taking the catch after running in from long-on.
Kallis and Boucher then set about the Pakistan bowling. Boucher had a successful Test series in surpassing Ian Healy's all time record for Test catches and making some vital knocks with the bat.
He bludgeoned 78 runs off only 38 balls in an innings that contained nine fours and four sixes although he was dropped by Younis on 24. It was his 20th ODI 50.
He was out when he played the ball to Inzamam at cover off the bowling of Naved-ul-Hasan. He had put on 128 runs with Kallis in 10.2 overs.
Naved-ul-Hasan then got the wicket of Kemp for 11 with Akmal taking a catch and at the close Kallis was unbeaten while Pollock had made two.
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