Anthony Joshua was able to block out jeers and boos from the O2 Arena crowd to produce a thunderous seventh-round stoppage against Robert Helenius and stay on track for a future bout with Deontay Wilder.
Joshua had been set to face fellow British heavyweight Dillian Whyte until his rival had to be pulled from the show last weekend when "adverse analytical findings" were detected in his doping test.
Helenius stepped in as a last-minute opponent, but the pre-match focus was on what next for Joshua with talks taking place with Wilder's camp over a fight in the new year.
It would only happen if Joshua could navigate the Finnish veteran and a slow start to proceedings in London saw whistles followed by boos in round three and further jeers occurred at the end of round six.
Joshua was able to provide the crowd with a speculator finish, unleashing a huge right hand to knock Helenius off his feet after one minute and 27 seconds of round seven.
There was brief concern over Helenius, who remained motionless, and it saw Joshua leave the ring to celebrate with the fans, but his opponent was able to get back up to his feet before the two fighters touched gloves.
While Joshua was coy over what next, promotor Eddie Hearn revealed plans to fight Wilder next and current world heavyweight champion Tyson Fury later in 2024.
Hearn said: "It is the fight we want. We have a three-fight plan.
"It was Helenius, first Dillian Whyte and then Helenius, and now Wilder and then Tyson Fury. That is the ambition."
Meanwhile, Joshua responded to his critics during a short interview in the ring.
"I just want to give a big round of applause for Robert Helenius for taking this fight," Joshua started off.
"People need to leave me alone. This is my time in the ring. Let me breath. The guy has got talent, I had to figure him out because he was a late replacement and I want to thank him for saving the show.
"I don't want to say too much. But my back hurts from carrying the heavyweight division." 130008 AUG 23
The sold-out were made to wait for Joshua after his compatriot Derek Chisora went the distance in his 10-round bout with fellow veteran Gerald Washington.
Chisora sustained a cut to his right eyebrow in the second round, but battled on despite blood regularly streaming down his face and ended victorious.
A few months shy of his 40th birthday and in his 47th fight, Chisora won for the 34th time by unanimous decision after the judges scored the contest 98-93, 97-94, 96-94.
Earlier in the evening, Filip Hrgovic stayed on track to take on Oleksandr Usyk with a last-round stoppage against Demsey McKean to remain mandatory challenger for the IBF belt.