Katie Taylor will face Delfine Persoon for the undisputed lightweight championship of the world on 1 June at Madison Square Garden in New York,
The lightweight fight is set to take place on the under-card of Anthony Joshua's fight with Jarred 'Big Baby' Miller.
It will be the third time Taylor has boxed on the same bill as her fellow London 2012 Olympic gold medal winner Joshua.
Taylor (13-0 6KOs) added the WBO title to her IBF and WBA crowns in March, stopping Rose Volante in the ninth round in Philadelphia.
Along with the WBA, IBF, WBO and WBC titles, Taylor and Persoon will battle for the Ring magazine belt – the first time the title has been on the line at lightweight for women.
UNDISPUTED!!!! @KatieTaylor will face Delfine Persoon for the WBC,WBA,IBF,WBO and RING World titles - June 1 @TheGarden live on @dazn_usa @SkySportsBoxing #allthemarbles 🇮🇪 🇧🇪🇺🇸 This is it! pic.twitter.com/GCokLuEYz7
— Eddie Hearn (@EddieHearn) April 16, 2019
"It's great that she has finally signed for the fight and I'm delighted that Eddie has been able to make it," said Taylor.
"After my fight last month I went back home for a week but then it was straight back to Connecticut to start the hard work in training camp for this fight.
"When I turned professional my first goal was to win a world title but then my next priority was to become undisputed champion so obviously this fight gives me the opportunity to do that so it's massive for my career.
"Women's boxing is in such great place right now and these are the kind of super fights that will really take it to new heights.
"Persoon is recognized as one of the best in the world pound for pound and has been the WBC champ now for over five years so it's the best against the best. Madison Square Garden seems like the perfect setting for a fight of this magnitude."
Persoon is undefeated for nine years and is 43-1 for her career to date.
She has held the WBC strap for five years with nine defences in that reign and the Belgian star fights outside of Europe for the first time in her career as she joins Taylor in aiming to cement her spot as the number one.
"This is a very unique opportunity for me and I’m thankful we’ve got the fight made," said Persoon.
"I did not have the opportunity to participate in the Olympic Games and now I get the chance to compete with the Olympic champion in Katie Taylor.
"I expect this will be a very tough and honest fight, and that the best boxer may win this title fight – and I expect that to be me."