Manny Pacquiao will defend his WBA world welterweight title against Adrien Broner on 19 January in Las Vegas.
Pacquiao has held world titles in eight divisions from flyweight to light-middleweight and is set to continue his glittering career in what will be his 70th professional contest.
The 39-year-old had been linked with a return bout against rival Floyd Mayweather as well as a showdown against British fighter Amir Khan, but announced on Twitter he will instead take on Broner.
Pacquiao captured a secondary welterweight crown - Keith Thurman is the WBA's Super champion - by stopping Lucas Matthysse in the seventh round of their fight in Kuala Lumpur in July.
The Filipino improved his record to 60 wins, seven defeats and two draws, but is 5-5 in his last 10 professional contests.
Broner, a former super-featherweight, lightweight, light-welterweight and welterweight world title holder, was once considered the heir apparent to Mayweather.
The brash American's speed and power carried him to 27-0 but he has since lost his way and has suffered three defeats in his last 10 outings.
He has fought only once this year: in a majority draw against Jessie Vargas in April.