Olympic gold medalist Sydney McLaughlin broke her own women's 400 metres hurdles world record at the US championships in Eugene, Oregon, on Saturday, winning the final in 51.41 seconds.

The 22-year-old took the lead early and never gave her opponents a chance, clinching her spot in the world championships in front of an adoring crowd.

"I was just gonna finish the race, knew anything was possible," she said.

Britton Wilson finished 1.67 seconds behind with Shamier Little taking third in 53.92.

"We're going to represent the USA well, we're all going to try to get on the podium," said McLaughlin.

She previously set the record with a 51.90-seconds performance at the US Olympic trials a year ago, only to shatter that figure in Tokyo, collecting gold in 51.46.

McLaughlin, who picked up silver in the event in 2019 in Doha, faces a potential showdown at worlds with chief rival and reigning champion Dalilah Muhammad, who was absent from the national championships due to injury.

The top three finishers in Eugene, Oregon, who meet certain qualifying standards, and reigning global title-holders will compete at the world championships, which will be held in the United States for the first time from 15 July at the same track.