A primary school in Co Offaly has been closed following confirmation of 23 cases of Covid-19.
The HSE has been carrying out a public health risk assessment at Scoil Bhríde in Edenderry over the past two days, and the situation has been described as "evolving".
The Department of Public Health Midlands said it is monitoring developments closely and has identified all children and staff who are close contacts of people with Covid-19.
There are over 300 pupils in the school including several classes for children with special needs.
In a letter to parents and guardians, the HSE said the health and safety of all staff and pupils is of the utmost importance.
"A large number of children and staff have been identified as close contacts of people with Covid-19. This has meant a number of staff members are unable to work as they are close contacts. This has made it challenging for the school to maintain safe ratios of staff to pupils"
Scoil Bhríde is to remain closed until 5 May, with teaching being moved to online platforms.
Two Kildare schools dealing with Covid-19 outbreaks
Two secondary schools in Newbridge, Co Kildare are dealing with Covid-19 outbreaks after a number of cases were identified amongst their students or staff.
Patrician Secondary School - an all-boys catholic secondary school - has asked all Transition Year students to stay away from the school and learn remotely from today until Friday 7 May.
The move comes after the HSE's Public Health team identified all transition year students in the school as close contacts because of a number of positive cases in that cohort.
All TY students in the school are being asked to stay at home and restrict their movements, and are being given two appointments for PCR tests.
The result of the second test is expected by Wednesday 5 May, and students who receive two negative test results will no longer have to restrict their movements.
Those with two negative tests will be allowed to return to school on Monday 8 May.
The Holy Family girls-only secondary school in the town says two year groups in the school have identified as close contacts, and the HSE is advising how long each student must stay out of school.
Parents are being advised through an App and through their mobile phones.
Additional reporting: Colman O'Sullivan