Around 300 direct jobs are under threat at delivery and logistics company Nuvion Group which has entered receivership.
It is understood hundreds of additional jobs could be affected among subcontractors, franchisees and solo operators across the delivery network.
Nuvion Group includes Parcel Connect, Fastway Couriers Ireland and Nügo.
A spokesperson for the company said the business has faced sustained inflation, rising operating costs and ongoing price pressures across the parcels market, which have made it no longer viable in its current form.
Mark Degnan and Brendan O'Reilly of Interpath Advisory have been appointed as receivers.
"Delays and disruption are envisaged and the receivers will work with retailers to minimise such delays," the spokesperson said.
"We want to sincerely thank our employees, franchisees and customers for their continued understanding and support during this difficult time," the company added.
