The Digital Hub has teamed up with Teen-Turn to address what it describes as the "gender skill gap" within second level education.
Recent data from the Department of Education found that only 20% of girls' secondary schools offer computer science, while research from the State Examinations Commission showed that 14% provided physics in Ireland in 2019.
The Higher Education Authority found that 86% of male students study practical subjects during senior cycle including engineering, building construction, design graphics and technology.
Less than 5% of girls in secondary schools nationwide study these subjects at all.
Teen-Turn Plus aims to expand educational and career opportunities available to girls in Dublin 8.
A new pilot project, Teen-Turn Plus is taking place each week from February to May, and August to November at The Digital Hub, which will provide hands on exposure to advanced scientific and technology topics in AI, physics and object-oriented programming.
The initiative is open to Teen-Turn participants attending secondary school in Dublin 8 or whose home residence is nearby.
"Levelling the playing field in the transition from second to third level education has never been more important as careers in STEM continue to see the highest demand from graduates," said Joanne Dolan, Teen-Turn co-founder.
"Teen Turn Plus is aiming to expand the horizons of girls in second level education and increase equal participation in STEM subjects," she added.
Fiach Mac Conghail, CEO of The Digital Hub said he looks forward to seeing the pilot programme develop.
"Equality, diversity and inclusion is an important part of our operations here at The Digital Hub, and it has been a pleasure to work with Teen-Turn over the years in ensuring that EDI in education is delivered to schools in our area," he said.