Chambers Ireland has called on businesses to support vaccinations, both of their staff and in the developing world.
Ian Talbot, its chief executive, said the reintroduction of restrictions has been a "shattering blow" to morale in many sectors of the economy.
"But there are positive signs, both in the effectiveness of booster vaccinations and in the demand for them," he added.
"Some of our members are volunteering in vaccination centres, and from what they tell us, large numbers of previously unvaccinated people, and incompletely vaccinated people, are overcoming their reticence and are finally getting the jab," he added.
However, Mr Talbot said members are also saying that some employers are requiring their employees to forego wages or take annual leave to facilitate vaccination.
"This is reckless and damages the very businesses that are struggling most, every vaccine makes us stronger," he said.
He said this is true on the international stage too.
"Chambers Ireland are members of the UNICEF Corporate Vaccine Alliance and urge all our members, and all other businesses in Ireland, to contribute to their efforts in vaccinating the world," Mr Talbot said.
