A messy Brexit could have "significant consequences" and represents the biggest short-term risk to the British economy, although all Brexit outcomes imply costs, IMF chief Christine Lagarde has said.
"All likely Brexit outcomes will involve net costs for the UK economy.
"But the higher the impediments that arise in the new relationship with Europe, the higher the cost," Christine Lagarde said.
Just a few weeks remain before Britain is due to leave the European Union at the end of March, but the government of Prime Minister Theresa May is still seeking changes to her Brexit deal in order to win backing from parliament.
Ms Lagarde said the "most significant near-term risk to the UK economy" was leaving the EU without a deal and a framework for the future relationship with Europe.
She added that others in Europe will be affected by Brexit to "varying degrees."
"Ireland, of course, and others such as the Netherlands, with a close relationship to the UK," she said.
Portugal, whose largest tourist market is Britain, would also be hit if Brexit is disorderly.
"Important trade and tourism links could be disrupted, and a loss of financial market confidence outside your borders could lead to higher sovereign and bank interest rates, which would weigh on growth," Lagarde said.
Turning to the global economy, Lagarde repeated previous statements that the expansion is slowing down faster than expected.
"We are not staring at a recession, but downside risks have clearly risen," she said, listing rising trade tensions, high global debt levels and slower growth in China.
Lagarde said a transition of the Chinese economy to more sustainable growth is positive, but there is a risk that the deceleration is "faster than expected."
"Even if new stimulus in China is effective, it is being targeted at relatively less import-intensive activities, so the rest of the world might still feel a deceleration," she said.
The IMF chief made her comments at Portugal's state council. She had been invited to participate in the state council - the Portuguese president's highest consultative body - which had gathered to discuss Brexit.