Warren Buffett's Berkshire Hathaway has disclosed a new stake in generic drugmaker Teva Pharmaceutical Industries.
The company also said it bought more shares of Apple, surpassing Wells Fargo & Co as its largest common stock investment.
Berkshire also nearly completed its yearlong exit from IBM, selling more than 94% of what was left from an investment Buffett has admitted was not among his best.
In a regulatory filing detailing its US-listed stock holdings as of December 31, Berkshire reported owning about 18.9 million Teva American depositary receipts, worth about $358m.
Teva shares rose more than 10% after market hours, reflecting what investors perceive as Berkshire's seal of approval for the Israeli drugmaker.
Last month, Berkshire said it would work with Amazon.com and JPMorgan Chase & Co to create their own healthcare company. Other healthcare stocks fell on that news.
The latest filing details investments made by Buffett and his investment deputies Todd Combs and Ted Weschler, though it does not say who bought what.
Combs and Weschler are generally responsible for Berkshire's smaller investments.
Berkshire's Apple stake grew by about 23% since the end of September to roughly 165.3 million shares worth $28 billion. That was just above the reported $27.8 billion stake in Wells Fargo.
Berkshire may have funded the Apple purchases by selling roughly $5 billion of IBM stock, reducing that stake to just 2.05 million shares worth about $314m.
Buffett began selling IBM in the first quarter of 2017, and has admitted he did not value the company as highly as when he began buying six years earlier.
Berkshire at one time owned roughly 81 million IBM shares, for which it paid about $13.8 billion. Berkshire was close to break-even on IBM when the selling began.
Berkshire also reported higher stakes in Bank of New York Mellon, Monsanto and US Bancorp and lower stakes in American Airlines Group, General Motors, France's Sanofi and Wells Fargo.
Earlier this week, Berkshire agreed to sell more than 43% of another big holding, Phillips 66, back to the oil refiner for $3.3 billion. It plans to remain a long-term shareholder.