Taoiseach Leo Varadkar has appointed Heather Humphreys as the new Minister for Business, Enterprise and Innovation. She replaces Frances Fitzgerald.
Ms Humphreys previously held the Culture, Heritage and the Gaeltacht portfolio since June.
She has also served as Minister for Arts, Heritage, and the Gaeltacht Affairs from July 2014 to May 2016; and Minister for Arts, Heritage, Regional, Rural and Gaeltacht Affairs from May 2016 to June 2017.
Announcing the appointment, the Taoiseach cited Ms Humphreys' background in business.
Meanwhile, Mr Varadkar also named Simon Coveney as the new Tánaiste, also replacing Frances Fitzgerald.
The Cork man, who was Mr Varadkar's rival for the Fine Gael leadership earlier this year, will also continue to serve as Minister for Foreign Affairs and Trade with responsibility for Brexit.