The European Investment Bank is expected to examine support for sectors of the Irish economy which are most affected by Brexit - including exporters and agriculture.
The EIB, the world's largest international public bank, is also expected to strengthen backing for transport, education, housing, healthcare and small business investment in Ireland.
This follows the meeting of the Ireland-EIB Financing Group at the bank's headquarters in Luxembourg.
The Ireland-EIB Financing Group was established last year with the opening of the EIB's first permanent presence in Ireland.
It aims to strengthen cooperation between the European Investment Bank and Irish Government Departments.
Two days of discussions this week were led by Finance Minister Michael Noonan, Minister for Public Expenditure and Reform Paschal Donohoe, European Investment Bank President Werner Hoyer and Vice-President Andrew McDowell.
The talks brought together senior officials from Government, the EIB's financing and advisory teams and the European Investment Fund.
"Continued discussions with the President Hoyer and EIB colleagues, strengthened in recent months through the appointment of Andrew McDowell as the first Irish Vice-President in 12 years, the new EIB Dublin office opened by the Taoiseach in December and structured partnership through the Ireland-EIB Financing Group is already unlocking support for new investment," commented Minister Noonan.
"I am confident that following today's meeting, the EIB will intensify its consideration of how to support projects crucial for Ireland's future such as social housing, ports, community nursing homes, improvements to the national road network, Dublin Metro North in the years ahead," he added.
The European Investment Bank is Europe's long-term lending institution and is owned directly by the 28 EU member states. It has provided over €6.8 billion over the last ten years for long-term investment across Ireland.
The EIB has invested in education, energy, transport, social housing healthcare, agriculture and water projects, as well as investment by small business and corporate research and development.