UK pharmacy chain Boots is to axe 700 jobs as it bids to simplify its structure across its non-store roles.
The UK retail giant said it will begin talks with affected staff in due course.
However, the firm added that it would put additional resources into its digital unit.
The cuts come months after the mega-merger between owner Alliance Boots and US pharmacy group Walgreens.
The company employs more than 108,000 staff in more than 25 countries, and has several stores in Ireland.
Boots president Simon Roberts said: "I believe this plan will make Boots even better for our customers and drive sustainable future growth."
About half of the cuts will fall at the firm's UK head office in Nottingham, and will include support and administrative staff. In total the headquarters has 4,000 staff, while the group employs 60,000 in the UK across nearly 2,500 stores.
The company said the purpose of the plan was to "bring together and simplify how resources are used".
It added that it expects to achieve the cuts through a mixture of natural attrition, redeployment, retraining and redundancies.
In December Alliance Boots completed its mega-merger with America's Walgreens.
It was announced in August that the US firm would take full control of the Boots the Chemist owner in a £9 billion cash and shares deal to swallow up the 55% of the company it did not already own.
The new group, Walgreens Boots Alliance, is based in Chicago but the headquarters of Boots remains in Nottingham, where its founder, John Boot, first opened a herbalist shop in 1849.
Walgreens has said a programme of cost-cutting would target £600m of savings by 2017.
In March, Boots also said it would cut 700 jobs after pulling the plug on 12 health and beauty outlets branded Wellbeing Services less than three years after the stores were launched.