165 jobs are to go at medicare company Conor Medsystems in Athlone, Co Westmeath.
The US company is located in the IDA industrial estate on the Dublin Road in the town.
The company has terminated tests for its coronary stent CoStar. It said last week that the stent had failed to meet targets and it would not be asking the US Food & Drug Administration for pre-market approval for the product.
