Enterprise Ireland, which helps Irish companies develop abroad, says it expects a more turbulent international business environment this year.
It says there is a critical need for companies to explore new markets.
Chief executive Dan Flinter says the US economic slowdown will make it more difficult for Irish firms to raise capital. But he adds that, as of now, there are no indications of a decline in the order books of client companies.
Mr Flinter was speaking at the launch of Enterprise Ireland's end of year statement.
The state body made £80m last year from investing in Irish companies. This included a £25m profit from the sale of Iona shares, £25m from the sale of Parthus shares and £4m from the sale of Trintech shares.
The chief executive said the investment performance in 2001 will not match that of last year because of the decline in US stock markets.
Exports from Enterprise Ireland companies grew 6.5% last year to £10bn. Sales climbed 7% to £21bn.