Emily Atack has said she is subjected to "relentless and disgusting" threats online that have led her to call the police and "question my entire existence at times".
The Inbetweeners star, 32, who has 1.8 million followers on Instagram, said she is targeted with around 200 harassing messages on social media a day, including those that threaten her safety.
Atack said she has had to move home four times in the wake of targeted abuse, telling The Sun on Sunday: "They knew where I lived, said what they were going to do to me, even my family.
"I got the police involved."
She added there is one man who creates new accounts every time she blocks him, telling the paper: "He's relentless and disgusting - beyond anything you can imagine. Yet he says he's a married man with children."
Atack said the threats appear in her direct messages "where I can't avoid it".
"It feels shameful," the British star continued.
"It has made me question my entire existence at times, and how men see me."
Atack says she is now calling on social media companies to clamp down on explicit comments online.
"It is assault and abuse.
"I should have the right to be able to go in there (to her direct messages on Instagram) safely," she said.
"More needs to be done to protect women."
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Source: Press Association