British comedian Sean Lock has died of cancer at the age of 58, his agent has announced.
The 8 Out Of 10 Cats team captain was best known for his surreal content and deadpan style.
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He also wrote and starred in the popular BBC sitcom 15 Storeys High.
A statement from his agent, Off The Kerb Productions, said: "It is with great sadness that we have to announce the death of Sean Lock.
"He died at home from cancer, surrounded by his family.
"Sean was one of Britain's finest comedians, his boundless creativity, lightning wit and the absurdist brilliance of his work, marked him out as a unique voice in British comedy.
"Sean was also a cherished husband and father to three children.
"Sean will be sorely missed by all that knew him.
Incredibly sad to learn of the loss of one of our greatest comedians, Sean Lock. A much loved part of the C4 family he's played a huge role on the channel for over 2 decades, and we’ll miss him. Our thoughts are with his family and friends pic.twitter.com/HrT6mjZLjT— Channel 4 (@Channel4) August 18, 2021
"We kindly request that the privacy of his family and children is respected at this difficult time."
Lock is survived by his wife Anoushka Nara Giltsoff, with whom he shared two daughters and one son.
Comedian Lee Mack, who was a close friend, paid tribute saying: "I've known this day was coming for some time, but it's no less heart-breaking.
"A true original both in comedy and life. I will miss him so much."
Born in Woking, Surrey, the comedy star left school in the early 1980s and began working on building sites but developed skin cancer, which he blamed on over-exposure to the sun. He made a full recovery and focused on a career in comedy.
One of his first professional TV appearances was in 1993, starring alongside Rob Newman and David Baddiel on their signature TV show Newman And Baddiel In Pieces.
He script-edited the 1998 BBC Two series, Is It Bill Bailey? and had his own show on BBC Radio 4 called 15 Minutes Of Misery, which was later expanded into TV series 15 Storeys High.
The show was set in a tower block and centred on a pessimistic character called Vince (played by Lock) and his flatmate Errol, played by Benedict Wong.
In 2005 Lock became a regular team captain on the panel show 8 Out Of 10 Cats, a role he held for 18 series.
Between 2006 and 2007 he hosted Channel 4 series, TV Heaven, Telly Hell, in which he invited celebrities to share their own selection of TV's triumphs and tragedies.
Guests on the show included Alan Davies, Johnny Vaughan, David Mitchell, Bill Bailey, Johnny Vegas and Nick Hancock.
Speaking at the time, Lock told the PA news agency: "I think one of my all-time favourite shows is Catchphrase with Roy Walker. I loved it. I used to like Roy's restraint, because, for a comedian, the opportunity to take the mick out of some of the ridiculous answers could have been too hard to resist."
Lock also appeared on panel shows including Have I Got News for You, QI, and They Think It's All Over.
In 2000 he won the gong for the best live stand-up at the British Comedy Awards.
Tributes have been paid to the comedian:
Brutal news about Sean Lock today.— Jimmy Carr (@jimmycarr) August 18, 2021
I loved him. I'm watching clips of him right now - laughing & crying. I’ll miss him so much.
This is desperately sad news. Such a brilliantly funny man. https://t.co/SINgJqvkFI— Dara Ó Briain (@daraobriain) August 18, 2021
So sorry to hear this. Farewell Sean, you brought a wonderful comedic talent to the world and you will be missed -— Eddie Izzard (@eddieizzard) August 18, 2021
Sean Lock: Comedian and 8 Out Of 10 Cats panellist dies from cancer aged 58https://t.co/up38yGeYKq pic.twitter.com/7IF7S5W6H9
I wish I had the words to describe the exceptional man that was Sean Lock. But today I don't, and I think he might have liked it that way.— Susie Dent 💙 (@susie_dent) August 18, 2021
I texted him couple of weeks ago and I'm now so glad I did. If you’ve a friend who’ve you not spoken to for a while, drop them a message and check in. It could be the last time. RIP Sean ❤️ pic.twitter.com/lePue0mRYw— Jason Manford (@JasonManford) August 18, 2021
I spelt Loch incorrectly then. Which sometimes doesn't matter but today it does, sorry Sean Lock. Loving seeing my timeline filled with love for you and some of your most brilliant comedy clips.— Gabby Logan (@GabbyLogan) August 18, 2021
Rest in peace Sean Lock. A true natural comedian who taught me so much x— David O'Doherty (@phlaimeaux) August 18, 2021
I idolised Sean as a comic long before I became a comedian myself and ten years working alongside him didn't diminish that in the least. An incredible comic brain and a truly unique voice. pic.twitter.com/4ZH8HRQrIU— Jon Richardson (@RonJichardson) August 18, 2021
It's heartbreaking to lose my dearest friend Sean Lock , he was a true original, a wonderful comic. All my thoughts are with his family.— Bill Bailey (@BillBailey) August 18, 2021