Friday night's Late Late Show will feature two powerhouses of Irish comedy - Pat Shortt and Tommy Tiernan.
They will chat to Ryan about joining forces for the gritty black comedy Dark Lies the Island. The film's set in a small Irish town over a week-long period, and also stars Moe Dunford, Peter Coonan and Charlie Murphy.
Rising star of the airwaves and of screen, Doireann Garrihy will discuss the biggest year of her career to date, as well as dealing with online bullies. She will also impersonate some of the well-known Irish faces that feature in the second season of The Doireann Project.
Former Irish football international Kevin Kilbane will be in studio to discuss feeling Irish while living in Britain during the Brexit era, his love of Mayo gaelic football, and his devastation at the loss of his father.
He has also just been unveiled as one of the upcoming contestants on ITV's Dancing On Ice, and will predict whether his football skills will transfer to the ice.
This Friday features a special performance from Moya Brennan, along with the RTÉ Philharmonic Choir, ahead of receiving her Lifetime Achievement Award at the upcoming RTÉ Radio 1 Folk Awards.
There will also be a debut performance of the new single from Hudson Taylor.
The Late Late Show, Friday, at 9.35pm on RTÉ One