TV and radio star Chris Evans shared the news on his BBC Radio 2 breakfast show when he asked listeners did they have any advice about having twins.
The 52-year-old broadcaster also revealed that Natasha had been undergoing IVF fertility treatment in the hopes of having another baby.
Evans said: "Mrs Evans is, she is. Double trouble, twin turbo. We have known for a while, obviously. She is definitely the mother, no doubt about that."
Watch out 2018, The Evans Twins are on the way... 👶👶@achrisevans finds out if Mrs Evans needs to eat for 3 and what pregnancy cravings actually mean from @henriettanorton https://t.co/arZ7DgciKO pic.twitter.com/sGIYO6blqG
— BBC Radio 2 (@BBCRadio2) April 16, 2018
Chris and Natasha have been married since 2007 and are already parents to sons Eli, five, and nine-year-old Noah.
Chris is also a father to daughter Jade, from his previous relationship with Alison Ward.
Evan said he had tried to break the news to their five-year-old son Eli.
He said on the show that the little boy "has got a shock and a half coming, he’s got a double shock coming".
He added: "We tried to tell him, he doesn’t quite get it yet. Eli is mum’s best mate. That is going to change, my friend."
"I’m looking forward to lots of curries and cravings."
Chris become a first-time grandfather in January 2015, following the birth of Jade's son Teddy.