Bobbi Kristina Brown, the only child of late singer Whitney Houston, has died at the age of 22, some six months after suffering irreversible brain damage in an incident at her Atlanta home, her family said in a statement.
Ms Brown, whose father is R&B singer Bobby Brown, was found face down and unresponsive in a bathtub in her home by her partner and a friend on 31 January. She was moved by her family to hospice care on 24 June.
"She is finally at peace in the arms of God," her family said. "We want to again thank everyone for their tremendous amount of love and support during these last few months."
Her death came three years after her Grammy-winning mother, who had battled substance abuse, drowned in a bathtub in a Beverly Hills hotel at age 48.
Authorities said cocaine abuse and heart disease contributed to Ms Houston's death on 11 February 2012.
Bobbi Kristina Brown inherited her mother's fortune.
A $10m civil lawsuit filed last month accuses Bobbi Kristina Brown's partner, Nick Gordon, of causing her life-threatening injuries and of stealing from her bank account while she was in a coma.
No one has been charged in the case.
Ms Brown was an aspiring singer who began performing with her mother as early as 1999, singing duets of My Love is Your Love.
Nick Gordon and Bobbi Kristina Brown
In 2003 they recorded another duet of Little Drummer Boy for a Christmas album.
Ms Brown's father is a Grammy Award winner who started his career as frontman for the R&B group New Edition.
Ms Houston and Mr Brown both struggled with substance abuse and divorced when their daughter was 14.
Ms Houston described their 15-year marriage, which ended in 2007, as drug- and alcohol-fuelled.
The couple's tempestuous relationship and often erratic behaviour was chronicled in the short-lived television series, Being Bobby Brown.
Bobbi Kristina Brown was hospitalised twice with anxiety after her mother's death.
In 2012 she starred on Lifetime's reality TV show, The Houstons: On Our Own, in which Houston's family struggled to recover from the famous singer's death.
The same year Bobbi Kristina Brown guest-starred on For Better or Worse, a television series about a married couple.