Comedian Joan Rivers remains in a critical condition after doctors placed her in a medically induced coma following complications during an operation on her vocal chords.
The 81-year-old is reportedly on life-support after she went into cardiac arrest earlier this week during an operation to repair her vocal chords.
She was rushed to Mount Sinai Hospital, Los Angeles, in a critical condition on Thursday morning at 9.40am after she stopped breathing during a routine medical procedure at a nearby clinic.
TMZ.com reports they have been told by sources close to Rivers that the Fashion Police star is on life-support, but the family are still hoping she will bounce back and recover her full health.
Rivers' daughter Melissa, has released a statement thanking everyone for their messages of support. She said: "My mother would be so touched by the tributes and prayers that we have received from around the world.
"Her condition remains serious but she is receiving the best treatment and care possible. We ask that you continue to keep her in your thoughts as we pray for her recovery."
Friends of the star, including her E! colleagues, Kelly Osbourne and Giuliana Rancic, have been posting their messages of support on Twitter.
4 the first time in years I got down on my knees & prayed tonight! I encourage U 2 do the same 4 @Joan_Rivers my grandma! #inconsolable
— Kelly Osbourne (@KellyOsbourne) August 30, 2014
Praying for @Joan_Rivers and @MelRivers. Even though Joan's the strongest woman I know, every single prayer counts. I love you, Joan
— Giuliana Rancic (@GiulianaRancic) August 30, 2014
@joan_rivers Please come back to us young lady. Your inimitable genius and compassion keeps a world you set … http://t.co/EoUzIXwtlM
— Charlie Sheen (@charliesheen) August 29, 2014
We can't lose Joan. All love and healing wishes to Her Majesty Joan Rivers- being ripped a new one by you is an honor to be treasured.
— Lena Dunham (@lenadunham) August 31, 2014
Can't stop thinking of @Joan_Rivers and hoping that @MelRivers is staying strong. My times with her in NY are some of my most favourite...
— Antony Cotton (@antonycotton) August 31, 2014
Thinking and praying for Joan Rivers #JoanRivers #MelissaRivers You are a fighter Get Well @Joan_Rivers pic.twitter.com/gwhFbnAc15
— Jerry Springer (@jerryspringer) August 30, 2014
I really need Joan Rivers to be ok.
— Seth Rogen (@Sethrogen) August 30, 2014