E! News co-host Giuliana Rancic and her husband Bill have thanked fans for their "love and support", following the news that their surrogate miscarried their second child.

The 39-year-old television personality and her entrepreneur husband were left ''shocked and saddened'' after their surrogate, who also carried their 21-month-old son Duke, suffered a miscarriage at nine weeks.

Rancic said in a statement: ''Bill and I want to grow our family more than anything else, so as you can imagine we were shocked and saddened when we received the bad news.

''We are incredibly appreciative of all the love and support from our viewers who have been on our journey for the past seven seasons and hope to have good news to share with everyone soon."

Rancic added: ''We have had our share of ups and downs and our faith is strong therefore we know in the end, everything will be OK.''