The Saturday Night Show on RTÉ One at 9:55pm will take the #NoMakeUpSelfies craze up a level when Amanda Brunker, Nuala Carey, Norah Casey and Daniella Moyles appear without make-up to help the Irish Cancer Society.
Also on Saturday's show, journalist Nell McCafferty will talk to host Brendan O'Connor about regrets, feminism and lessons she has learned as she turns 70.
After his candid video last week, TV presenter Eoghan McDermott will discuss why he self-harmed.
The up-and-coming Morrissey and Marshall will be the musical guests on the night.