Jamie Lee Curtis is set for a return to television with the announcement that she will start in a new medical reality drama for CBS.

The Hollywood Reporter says she will play the lead role in the new David Marshall Grant drama.

The show is based on an Israeli format, Rat Quartet, and is based around quadruplets who grew up on a reality show.

Curtis will play the quadruplets’ mother who is a doctor running a hospital where one of her sons is also employed. She is tough and has never got over the fact that her husband died of a rare genetic disease which also could threaten her children’s lives.