Peep Show stars David Mitchell and Robert Webb said that they think the comedy has the potential to go on forever.
The actors - who have played flatmates Mark and Jeremy in the sitcom since 2003 - say that they can't see the series running out of material and coming to an end.
Mitchell told the new issue of Reader's Digest: "Two once-young men, now not quite so young, are living together and facing the problems that everyone faces.
"There's pretty much a bottomless pit of potential problems that we can cover."
He added that the relationship between their characters works so well because they can "look down" on one another.
Mitchell added: "Mark and Jeremy make each other feel better because they have someone to look down on.
"Mark thinks: 'My job is going badly, but not as badly as his', while Jeremy thinks: 'I haven't embraced the dream, but he has even less.'
Webb added of the pair's relationship: "Jeremy and Mark are almost like a married couple. At one point, Jeremy considers ditching Mark for another friend.
"He thinks, I could be in the mainstream instead of stuck with Mark in our own little puddle. But Jeremy and Mark will always remain in their own little puddle.
"They both think that, the moment they open the door, the party stops and everyone goes 'Shhh!' We all go through that feeling of being an outsider."
