Madonna is reportedly hoping to have a child with her boyfriend, Jesus Luz.
According to The Sun, the 51-year-old consulted doctors over conceiving another child after Luz, 22, told her that becoming a father would be his "greatest adventure".
It is thought that the popstar is convinced Luz will be a good parent and has told friends that she has "endless love" in her heart for another baby.
Referring to Madonna as her nickname Em, a source told the newspaper: "Em says motherhood is her greatest achievement and the most fulfilling thing in her life.
"She knows that, at 51, it's going to be harder to conceive naturally. But she is Olympic-athlete fit and is ready for the challenge."
The singer already has 14-year-old daughter Lourdes from her relationship with Carlos Leon and 9-year-old son Rocco by ex-husband Guy Ritchie. She is also mother to adopted children David Banda and Mercy James.
The source added: "Jesus is very religious and deeply in love with [Madonna]. He adores her kids but has always wanted a child of his own."