After 16 months as Executive Producer and 23 years with EastEnders, Lorraine Newman is leaving the soap and will be replaced by former story producer Dominic Treadwell-Collins.
Newman, who joined EastEnders as a script secretary at the age of 19 and has held every editorial role on the show, said: "I have loved every moment of my time at EastEnders but it is finally time to leave Walford."
She continued: "Over the past 23 years I have been involved in some of the best moments on British television, from 'Who Shot Phil?', to 'You Ain't My Mother!', to the 25th Live Anniversary episode and in the past year, the Olympic Torch episode has also been a proud highlight."
Newman added: "Over the past year, I have also had the pleasure of planning and implementing the revival of many of the EastEnders clans who should always be at the heart of the show.
"I am confident that I am leaving the show in a stronger place and am sure that Dominic will continue to build upon this, taking the show to a new level."
She concluded: "I am delighted to be joining BBC Drama Production as an Executive Producer and look forward to the new opportunities and projects this will bring."
Treadwell-Collins is returning to EastEnders after a three-year absence, during which he worked as Head of Development at production company Lovely Day.
He said: "You never really leave EastEnders - and for the past three years, the characters have all stubbornly stayed in my head. I'm sad to be leaving Lovely Day, especially at such a fertile time for the company - but am excited about the challenge of taking the helm of Britain's greatest drama.
"It is an honour to follow someone as talented and experienced as Lorraine and I'm looking forward to building on her work and taking this iconic and essential show into 2014 and beyond, as we look to EastEnders' 30th anniversary in 2015."