Arsenal v Hull
Arsenal are missing full-back Bacary Sagna for the clash with Hull at the Emirates Stadium.
Sagna has a hamstring injury so Carl Jenkinson is set to start, while striker Lukas Podolksi is expected back in training this week after recovering from a hamstring injury of his own.
Midfielders Alex Oxlade-Chamberlain and Abou Diaby remain sidelined with knee injuries.
James Chester is set for his first appearance since September for Hull.
Chester has been out with a hamstring problem for over two months but has trained for the past fortnight and looks set to replace the suspended Curtis Davies.
Striker Matty Fryatt also returns to the matchday squad having returned to the club following a loan spell at Sheffield Wednesday.
Last six league matches: Arsenal W W W L W W Hull L L W L L
Manchester Utd v Everton
Marouane Fellaini could be in line to face former club Everton for the first time as a Manchester United player.
Phil Jones is suspended and with Michael Carrick (Achilles) ruled out, Fellaini is the obvious replacement.
Robin van Persie has "a chance" of recovering from a combination of groin and toe problems.
Everton manager Roberto Martinez has no new injury worries ahead of the trip to Old Trafford.
Bryan Oviedo is set to continue deputising for injured left-back Leighton Baines (broken toe) after making only his second league start in 18 months against Stoke at the weekend.
Martinez's big decision is whether to retain on-loan Barcelona youngster Gerard Deulofeu after his impressive display against the Potters or bring back the safer option of Kevin Mirallas.
Last six league matches: Man Utd D W W W D D Everton W W D D D W
Liverpool v Norwich
Playmaker Philippe Coutinho is set to return to the starting line-up against Norwich at Anfield after only being fit enough for a place on the bench for Sunday's defeat at Hull.
After conceding three goals for the second successive game manager Brendan Rodgers is likely to change his defence with Kolo Toure the man who will probably make way for Daniel Agger, who was dropped at the KC Stadium.
Forward Iago Aspas was an unused substitute at Hull after returning to the squad after injury but after disappointing performances from Victor Moses and Raheem Sterling he may get a chance with striker Daniel Sturridge out until next month.
Norwich boss Chris Hughton has no fresh injury concerns for his side's visit to Anfield.
The Canaries are looking to build on their weekend win at home to Crystal Palace but are set to be without midfielders Anthony Pilkington (hamstring) and Robert Snodgrass (knee), while club-record signing Ricky van Wolfswinkel (toe) has targeted the Swansea game on 15 December for his return.
Elliott Bennett (knee), goalkeeper Mark Bunn and midfielder Alexander Tettey (both ankle) are all still sidelined.
Last six league matches: Liverpool D W L W D L Norwich L D L W L W
Sunderland v Chelsea
Defender John O'Shea has handed Sunderland boss Gus Poyet a major boost by training ahead of the home clash with Chelsea.
The Ireland international ended Saturday's 0-0 draw at Aston Villa with a groin problem, but appears to have recovered and is in line to retain his place.
However, keeper Keiren Westwood (shoulder) and defender Carlos Cuellar (hip) remain on the injured list and will not be involved once again.
Chelsea manager Jose Mourinho will be without Brazilian duo David Luiz and Oscar.
Luiz is still struggling with a knee injury while Oscar was forced off in Sunday's 3-1 win over Southampton with an ankle problem, although Mourinho is not expecting either player to be missing for too long.
Samuel Eto'o is back in contention following his groin injury with midfielder Marco van Ginkel (knee) the only long-term absentee.
Last six league matches: Sunderland L W L W L D Chelsea W W L D W W
West Brom v Manchester City
West Brom will be without midfielder Youssouf Mulumbu for their tussle with Manchester City at The Hawthorns.
Mulumbu is suspended for one game after collecting five yellow cards, with Claudio Yacob likely to step in as replacement.
Winger Scott Sinclair, on loan from City, cannot play against his parent club although he is out anyway with a hamstring problem, joining goalkeeper Ben Foster on the sidelines.
Manchester City captain and centre-back Vincent Kompany could return after 10 games out with a thigh injury.
Fellow defender Matija Nastasic, playmaker David Silva and striker Stevan Jovetic all remain on the sidelines with calf injuries.
Costel Pantilimon is likely to be retained in goal ahead of Joe Hart after impressing in Sunday's win over Swansea.
Last six league matches: West Brom D L W D D L Man City W L W L W W
Southampton v Aston Villa
Southampton goalkeeper Artur Boruc will miss the game against Aston Villa because of a broken hand, which could sideline him for up to six weeks.
Reserve Kelvin Davis is also unavailable, so Argentinian Paulo Gazzaniga will deputise having come on to replace Boruc in the 3-1 defeat at Chelsea on Sunday.
French midfielder Morgan Schneiderlin (groin) will miss out, while Uruguay international Gaston Ramirez is also not yet match fit along with defender Danny Fox and Brazilian midfielder Guly do Prado, who is a long-term absentee after undergoing knee surgery.
Paul Lambert will check on striker Andreas Weimann's fitness ahead of the trip to St Mary’s.
The Austrian experienced a tight hamstring in Saturday's goalless draw with Sunderland but is hopeful of being fit enough to feature.
Aside from long-term absentees Charles N'Zogbia and Jores Okore, Lambert has no other injury problems.
Last six league matches: Southampton D W D W L L Aston Villa L L D W D D
Fulham v Tottenham
Fulham right-back Sascha Riether will return from a three-match suspension for new manager Rene Meulensteen's first game in charge.
Forward Moussa Dembele will be assessed after picking up a minor hamstring problem in the 3-0 defeat at West Ham, which proved to be the final match of Martin Jol's tenure.
Defender Brede Hangeland could be back after a sciatic nerve problem, while striker Dimitar Berbatov is also expected to be fit following illness. Striker Hugo Rodallega (groin) and defender Matthew Briggs continue their rehabilitation.
Tottenham striker Emmanuel Adebayor is still struggling with a groin problem and is therefore a major doubt.
Midfielder Christian Eriksen (ankle), defender Danny Rose (toe) and striker Harry Kane (back) are all out.
Manager Andre Villas-Boas has to decide whether to keep faith with floundering forward Roberto Soldado, or recall Jermain Defoe.
Last six league matches: Fulham W L L L L L Tottenham W W D L L D
Swansea v Newcastle
Swansea manager Michael Laudrup will be without a host of injured players for the visit of Newcastle.
Wilfried Bony (hamstring) and Angel Rangel (calf) are sidelined with injuries suffered against Valencia, while Michu has not fully recovered from an ankle injury, meaning Alvaro Vazquez will again lead the line.
Garry Monk (knee) is also out but Michel Vorm could be back from a knee problem while Leon Britton is back in contention following a toe injury.
Newcastle boss Alan Pardew has no fresh injury problems ahead of the trip to south Wales.
Indeed, Pardew has the likes of Steven Taylor, Mapou Yanga-Mbiwa, Vurnon Anita, Hatem Ben Arfa and Papiss Cisse, who did not make the starting line-up for Saturday's 2-1 home win over West Brom, desperate to force their way into contention.
In addition, Massadio Haidara, Paul Dummett, Gael Bigirimana, Gabriel Obertan, Sylvain Marveaux and Sammy Ameobi all started Monday afternoon's 1-1 Under-21s' draw with Chelsea as they push for senior involvement.
Last six league matches: Swansea W D L D W L Newcastle D L W W W W
Stoke v Cardiff
Jonathan Walters' run of 102 consecutive Premier League starts for Stoke is under threat because of a thigh problem.
The striker is a doubt while defender Robert Huth and forward Marko Arnautovic will definitely miss out.
Huth has had a successful operation on his knee and could be back in three to four weeks while Arnautovic is still recovering from a hamstring strain.
Cardiff boss Malky Mackay is set to rotate his squad.
Craig Bellamy and Peter Odemwingie maybe set for starting roles having been on the bench for Saturday's defeat against Arsenal, with winger Craig Noone another possibility.
But striker Andreas Cornelius may have to wait for his first league start as Mackay looks to manage his return from a lengthy lay-off with an ankle injury.
Last six league matches: Stoke D L D D W L Cardiff L D W L D L