Gareth Bale started for Tottenham Hotspur for the first time in seven years and helped them to a 3-0 win over Austria's LASK in their first match of the Europa League group phase.
Lucas Moura opened the scoring after 18 minutes and Bale’s square pass was turned into his own net by Andres Andrade nine minutes later for a two-goal halftime lead.
Substitute Son Heung-min added the third in the 84th minute to ensure a winning start for Spurs to their Group J campaign.
Kemar Roofe made an almighty splash as his wondergoal ensured rain-lashed Rangers kicked-off their Europa League campaign with a 2-0 win over Standard Liege.
Gers had to endure a second-half downpour but Roofe's stoppage-time strike from the halfway line sank the Belgian outfit, with the former Leeds forward marking his first appearance in over a month due to an ankle injury in style.
54.6 - Kemar Roofe's goal for Rangers against Standard Liège was scored from a distance of 54.6 yards, the furthest distance ever for a goal scored in the UEFA Europa League. Spectacular. #UEL pic.twitter.com/71qN1QUtdq— OptaJoe (@OptaJoe) October 22, 2020
Leicester made the perfect start to their Europa League campaign after a comfortable 3-0 win over Zorya Luhansk.
James Maddison, Harvey Barnes and Kelechi Iheanacho struck to give the Foxes victory in their Group G opener.
Lior Refaelov scored the winner for Royal Antwerp, who saw off Ludogorets 2-1 in the other group game.
Napoli started their Europa League campaign with a shock defeat at home to AZ Alkmaar.
Alkmaar had travelled to Italy with 13 of their players sidelined because of coronavirus, but the Dutch runners-up were still able to spring a surprise against a side that reached the last 16 of the Champions League last season.
Dani De Wit scored the decisive goal at the Stadio San Paolo, finding space in the area before drilling beyond Napoli goalkeeper Alex Meret from close range after 57 minutes.
Real Sociedad also prevailed 1-0 in Group F, winning at Croatian club Rijeka following Jon Bautista's strike in time added-on.
A mistake by Arsenal goalkeeper Bernd Leno gifted a goal to Taxiarchis Fountas as Rapid Vienna went into a 51st-minute lead but the Gunners hit back to win 2-1 at at the Allianz Stadion, where 3,000 home fans watched on.
Arsenal scored twice in four minutes with Luiz levelling and substitute Aubameyang bagging the winner a quarter of an hour before full-time in Group B, where Norwegian champions Molde also won 2-1 after coming from behind to beat Irish side Dundalk.
Rade Krunic, Brahim Diaz and Jens Hauge were all on the scoresheet as AC Milan prevailed 3-1 at Celtic, who scored a consolation through Mohamed Elyounoussi, while also in Group H a hat-trick from Yusuf Yazici lifted Lille to a 4-1 victory over 10-man Sparta Prague.
AS Roma came back from a goal down to beat Swiss side Young Boys 2-1 away thanks to two goals in five second-half minutes by Bruno Peres and Marash Kumbulla in Group A.
Spanish clubs Granada and Real Sociedad enjoyed 2-1 and 1-0 away wins over PSV Eindhoven and Croatian side Rijeka in Group E and F respectively, while Benfica chalked up a 4-2 victory over Lech Poznan in Group D.