Shane Duffy proved his fitness and starts as Ireland take on Georgia in tonight’s Euro 2020 qualifier at the Aviva Stadium.
The towering centre-half hurt his ankle in Saturday’s 1-0 victory in Gibraltar and sat out training on Monday back in Dublin.
Duffy went for a precautionary scan on Monday afternoon and with a clean bill of health, the Brighton centre-half takes his place in the heart of the defence.
Seamus Coleman, once again, captains the side and joins Duffy in the back four, alongside Richard Keogh and Enda Stevens.
Glenn Whelan comes into the starting XI and will take on the holding role in midfield.
Aston Villa team-mate Conor Hourihane will join Whelan in the middle of the park, alongside Jeff Hendrick, who scored the match winner on Saturday.
David McGoldrick starts up front, keeping his place, following a composed performance on Saturday in appaling conditions at the Victoria Stadium.
Robbie Brady has been elevated to a place in the starting XI, having come on in the 57th minute for Matt Doherty.
The Wolves wing-back starts on the bench after the manager admitted that the experiment of playing the Dubliner in front of Coleman did not work on Saturday.
The only other change sees Sean Maguire dropped from the starting XI, with Whelan’s presence giving Ireland more players in the middle of the pitch, an area that caused problems on Saturday in the 4-4-2 formation.
McCarthy will most likely set out his team in a 4-3-3 formation with James McClean and Brady tasked with patrolling the flanks, while linking up with McGoldrick.
Georgia make three changes from the side that were beaten 2-0 to Switzerland on Saturday.
Soloman Kverkvelia, Otar Kiteishvilli and Vato Arveladze, replace Jano Ananidze, Jemal Tabidze and Valeri Qazaishvili.
Republic of Ireland: Darren Randolph; Seamus Coleman (capt), Shane Duffy, Richard Keogh, Enda Stevens; Glenn Whelan, Conor Hourihane, Jeff Hendrick; Robbie Brady, James McClean, David McGoldrick.
Georgia: 1. Giorgi Loria; 2. Otar Kakabadze, 3. Davit Khocholava, 4. Guram Kashla, 5. Soloman Kverkvelia, 6. Nika Kvekveskiri, 7. Jaba Kankava (capt), 9. Otar Kiteishvilli, 21. Valeriane Gvilia, 11. Giorgi Kvilitaia, 14. Vato Arveladze.