Oldham have the opportunity to complete a Merseyside double as the conquerors of Liverpool have been drawn to play city rivals Everton in the FA Cup fifth round.
Paul Dickov's side held out to beat Liverpool 3-2 on Sunday afternoon, and will welcome the Toffees to Boundary Park with a quarter-final spot up for grabs.
Leeds United, who beat Spurs this afternoon, have to travel to the home of Premier League champions Manchester City, while Manchester United will play host to Reading in the only all-Premier League tie of the round.
Reigning champions Chelsea must do it all again with Brentford after today's draw, and the winner's reward is a trip to Middlesbrough.
FA Cup fifth-round draw:
Huddersfield/Leicester v Wigan
MK Dons v Barnsley
Oldham v Everton
Luton v Millwall
Arsenal v Blackburn
Man City v Leeds
Man Utd v Reading
Middlesbrough v Brentford/Chelsea
* Ties to be played on the weekend of 16 and 17 February.