Garry Ringrose will captain Leinster in their first game away from Dublin since February's trip to the Gnoll, as they head to Italy to take on Benetton.
It's the same back three that started against Dragons last weekend with Hugo Keenan again selected at full back, Jordan Larmour on the right wing and James Lowe on the left.
In the centre Robbie Henshaw makes his first appearance of the new campaign in the number 12 shirt with captain Ringrose outside him.
Jamison Gibson-Park again starts at scrum-half with Ross Byrne his half back partner this week.In the pack Ed Byrne, James Tracy and Michael Bent will line up in the front row with Ryan Baird and James Ryan behind them to complete the tight five.
Leinster: Hugo Keenan, Jordan Larmour, Garry Ringrose, Robbie Henshaw, James Lowe, Ross Byrne, Jamison Gibson-Park,. Ed Byrne, James Tracy, Michael Bent, Ryan Baird, James Ryan, Caelan Dori, Will Connors
Replacements: Jack Conan, Seán Cronin, Cian Healy, Tom Clarkson, Ross Molony, Rhys Ruddock, Luke McGrath, Harry Byrne, Jimmy O'Brien
The Munster side to take on Edinburgh at Thomond Park shows seven changes to the side that defeated Scarlets in the thrilling opening round encounter in Wales.
Last week’s match-winner, Academy out-half Ben Healy, starts at 10 this weekend as he joins Craig Casey in the half backs.
There is a new midfield pairing with Alex McHenry, making his first Guinness PRO14 start, named alongside Rory Scannell.
In the back three Matt Gallagher makes his Munster debut on the left wing joining Andrew Conway and Mike Haley. Jeremy Loughman comes into the front row to pack down with Rhys Marshall and John Ryan while Fineen Wycherley joins Tadhg Beirne in the engine room.
The backrow change sees Tommy O’Donnell included with Jack O’Donoghue making the move to blindside, and CJ Stander captains the side from number 8.
Munster: Mike Haley; Andrew Conway, Alex McHenry, Rory Scannell, Matt Gallagher; Ben Healy, Craig Casey; Jeremy Loughman, Rhys Marshall, John Ryan; Fineen Wycherley, Tadhg Beirne; Jack O’Donoghue, Tommy O’Donnell, CJ Stander
Replacements: Kevin O’Byrne, James Cronin, Roman Salanoa, Gavin Coombes, John Hodnett, Conor Murray, Jack Crowley, Dan Goggin.
Marcus Rea will make his first start for Ulster on Saturday evening, in the trip to play Ospreys at Liberty Stadium.
The 23-year-old – who was Player of the Match in his sole previous Ulster appearance as a replacement against Leinster in April 2019 - has been named at openside flanker. Marcus's older brother Matty is named alongside him at blindside, with Marcell Coetzee once again packing down at number eight.
Jack McGrath, Rob Herring and Marty Moore have been given the front row starting berths, and Alan O’Connor has been selected along with captain Iain Henderson in the second row.
Matt Faddes returns to the starting side on the right wing and will join Jacob Stockdale at full-back and Rob Lyttle on the left wing. Last week’s midfield duo of Stewart Moore and James Hume has been retained. Ian Madigan comes in to start at fly-half, pairing with John Cooney at scrum-half.
Ulster: Jacob Stockdale, Matt Faddes, James Hume, Stewart Moore, Rob Lyttle, Ian Madigan, John Cooney, Jack McGrath, Rob Herring, Marty Moore, Alan O'Connor, Iain Henderson (Capt.) , Matthew Rea, Marcus Rea, Marcell Coetzee.
Replacements: Adam McBurney, Eric O'Sullivan, Gareth Milasinovich, Kieran Treadwell, Greg Jones, David Shanahan, Louis Ludik, Sean Reidy.
Connacht Head Coach Andy Friend has made two changes to his starting XV their clash against Cardiff Blues at Rodney Parade.
Eoghan Masterson comes in for his 93rd Connacht appearance, starting at blindside flanker. Captain Jarrad Butler moves to number 8 as a result while Conor Oliver retains his place on the opposite flank.
The other changes comes in the backs where Sammy Arnold partners Bundee Aki at centre.
The remainder of the team is the same that impressively saw off Glasgow Warriors last week, with hooker Dave Heffernan joined by props Denis Buckley and Finlay Bealham in the front row, while Gavin Thornbury and Quinn Roux continue their second row partnership.
Connacht: John Porch, Peter Sullivan, Sammy Arnold, Bundee Aki, Alex Wootton, Jack Carty, Kieran Marmion, Denis Buckley, Dave Heffernan, Finlay Bealham, Gavin Thornbury, Quinn Roux, Eoghan Masterson, Conor Oliver
Replacements: Jarrad Butler, Shane Delahunt, Jordan Duggan, Jack Aungier, Ultan Dillane, Paul Boyle, Stephen Kerins, Conor Fitzgerald, Tom Daly