This week Ryan spoke to mum-of-three Niamh on the pressures of home-schooling; Philomena Lee on her experience in Sean Ross Abbey mother-and-baby home; Wilfred Frost on the work of his father, legendary television host David Frost; And Dr Caro Verbeek on keeping history alive by reconstructing the smells of the past.
Star of Downton Abbey and Paddington, Hugh Bonneville, spoke to Ryan about portraying beloved children's author Roald Dahl in the Sky Arts film 'To Olivia' and how he's been helping out with the vaccine roll-out in the UK.
American actor Paul Oakley Stovall plays George Washington in the first national tour of 'Hamilton'. He joined Ryan on the line from Cork to talk about following in the footsteps of historical figure Frederick Douglass as part of plans for a new musical.
Ruth Coker Burks is someone who has defied disapproval in America's Deep South to help and care for men with Aids since the 1980s. She joined Ryan on the line from the US to tell her remarkable story of compassion and combating prejudice.