Disgraced Hollywood mogul Harvey Weinstein has pleaded not guilty in a courtroom in Los Angeles to all 11 charges of rape and sexual assault against five women in California hotel rooms.

The convicted rapist has been brought back to the city where he once presided over massive, industry-shaking film deals to face more charges that could result in an additional 140 years in prison.

"The not guilty plea is entered," said Judge Sergio Tapia, after an attorney spoke on behalf of Weinstein, who was present in the courtroom in a wheelchair and wearing a brown jumpsuit.

He has been serving a 23-year prison sentence for sexual assault in New York since last year.

Weinstein was transferred to Los Angeles yesterday for a second trial in which he will face new charges.

The once all-powerful Hollywood producer's downfall was seen as a major victory for the #MeToo movement.

The 69-year-old left the Wende prison in upstate New York and was handed over "to the appropriate officials for transport to the state of California per a court order," a spokesman for the New York prison authorities said in a statement.

Los Angeles police confirmed Weinstein "was brought to LA stemming from an extradition warrant that was issued for several felony sexual assault charges".

Legal efforts to stop the extradition in Los Angeles did not reach court.

"We are disappointed that the Los Angeles district attorney didn't wait for the judge's ruling, but we did expect this to happen at some point," Weinstein's spokesman, Juda Engelmayer, told AFP.

"We will be fighting so that Harvey can receive his needed medical care and, of course, so that he can be treated fairly."

According to California law, Weinstein's trial must begin within 120 days of his extradition, which would be in mid-November.